| Burbank Child Development Center | 265 Nichols Rd, Guayama, PR 00784 | Preschool |
| Busy Bees Preschool Center | 3 Harugari St, Guayama, PR 00784 | Center |
| Children's Aid Child Care Center | 1480 John Fitch Hwy, Guayama, PR 00784 | Preschool |
| Guild of St. Agnes - Fitchburg Preschool - School-Age | 62 Dover St, Guayama, PR 00784 | Center |
| MOC Child Care & Head Start Services Center - Hosmer | 110 South St, Guayama, PR 00784 | Preschool |
| MOC Child Care and Head Start Services | 133 Prichard St, Guayama, PR 00784 | Preschool |
| Maverick Street Family Center - Early Intervention | 98 Maverick St, Guayama, PR 00784 | Center |
| Messiah Lutheran Preschool | 780 Rindge Rd, Guayama, PR 00784 | Preschool |
| Montachusett Regional YMCA Preschool - Kindergarten & School Age | 55 Wallace Ave, Guayama, PR 00784 | Preschool |
| Sacred Heart Preschool and Child Care Center | 22 Cottage St, Guayama, PR 00784 | Preschool |
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| The Kid Stop | 184 Clarendon St, Guayama, PR 00784 | Preschool |