| Canton Community Kindergarten | 1541 Washington St, Holyoke, MA 01041 | Preschool |
| Champions at Dean S. Luce | 45 Independence St, Holyoke, MA 01041 | Center |
| Clarke School East | 1 Whitman Rd, Holyoke, MA 01041 | Center |
| Cole - Harrington Children's Center | 3 Randolph St, Holyoke, MA 01041 | Preschool |
| Cole - Harrington Early Learning Center | 960 Washington St, Holyoke, MA 01041 | Preschool |
| Cole - Harrington Infant Toddler Enrichment | 605 Neponset St, Holyoke, MA 01041 | Center |
| Cole - Harrington Kindergarten Enrichment Program | 55 Pecunit St, Holyoke, MA 01041 | Center |
| Fountain of Grace Academy | 427 Turnpike Street, Holyoke, MA 01041 | Preschool |
| June's Preschool Garden | 1508 Washington Street, Holyoke, MA 01041 | Preschool |
| Reebok Child Care Center | 1895 J W Foster Blvd, Holyoke, MA 01041 | Preschool |
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| The Gridley School | 314 Washington St, Holyoke, MA 01041 | Preschool |
| The Learning Circle Preschool | 3 Blue Hill River Rd, Holyoke, MA 01041 | Preschool |