| Abc Adventures Preschool And Child Care | 118 Industrial Drive, Louisburg, NC 27549 | Preschool |
| Almost Home Wee Care | 583 Flat Rock Church Road, Louisburg, NC 27549 | Center |
| Centerville Learning Center #1 | 3878 Nc 58 Hwy, Louisburg, NC 27549 | Center |
| Edward Best Elementary Before & After School Care | 4011 Hwy 56 E, Louisburg, NC 27549 | Center |
| Kid's Zone | 1996 Hwy 39 N, Louisburg, NC 27549 | Center |
| Little Angel's Child Care Center | 519 North Bickett Blvd, Louisburg, NC 27549 | Center |
| Louisburg Elementary Before & After School Program | 50 Stone Sutherland Road, Louisburg, NC 27549 | Center |
| Nelson Head Start Center | 102 Leonard Farm Road, Louisburg, NC 27549 | Preschool |
| Precious Beginnings Child Care Center | 119 Clifton Pond Road, Louisburg, NC 27549 | Center |
| Royal Elementary Before & After Enrichment Program | 308 Flat Rock Church Road, Louisburg, NC 27549 | Center |
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| Saint Paul Presbyterian Day Care | 928 South Main Street, Louisburg, NC 27549 | Center |
| The Kid's Corner | 205 Dogwood Rd, Louisburg, NC 27549 | Center |
| Vance Granville Childcare Daycare Center Franklin Campus | 8100 Nc 56 Hwy, Louisburg, NC 27549 | Preschool |