| La Petite Academy of Durham | 4022 Wake Forest Highway, Durham, NC 27703 | Preschool |
| 21st Century Child Care At Sherwood Park | 100 Wittenberg Way, Durham, NC 27703 | Center |
| A Bundle Of Joy Learning Center | 2944 Holloway Street, Durham, NC 27703 | Center |
| Alice In Wonderland Childcare Center | 2100 South Miami Blvd, Durham, NC 27703 | Center |
| Bethesda Child Care Center I | 1914 S Miami Blvd, Durham, NC 27703 | Preschool |
| Bethesda Sac Club | 2009 S Miami Blvd, Durham, NC 27703 | Center |
| Bright Horizons At Imperial Center | 1012 Slater Road, Durham, NC 27703 | Preschool |
| Bryant's Day Care Home | 904 Fiske Street, Durham, NC 27703 | Center |
| Calvary Child Care | 1204 Lynn Road, Durham, NC 27703 | Center |
| Deborah's Day Care | 1801 Stage Road, Durham, NC 27703 | Center |
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| Destiny's Way Day Care Home | 413 East End Avenue, Durham, NC 27703 | Center |
| Fellowship Baptist Daycare | 515 Southerland Street, Durham, NC 27703 | Center |
| Freeland Day Care Center #1 | 608 North Hyde Park Avenue, Durham, NC 27703 | Center |
| Kids R Kids RTP | 2502 Presidential Drive, Durham, NC 27703 | Center |
| Little People Day Care Center | 1020 Highway 70 East, Durham, NC 27703 | Center |
| Little Wonders Child Care Services | 3610 Wake Forest Hwy, Durham, NC 27703 | Center |
| Mcqueen's Amazing Changes Childcare | 124 Woodcrest Street, Durham, NC 27703 | Center |
| New Beginnings Home Child Care | 1834 Liberty St, Durham, NC 27703 | Center |
| Oak Grove Sac Club | 3810 Wake Forest Road, Durham, NC 27703 | Center |
| RN Harris Sac Club | 1520 Cooper Street, Durham, NC 27703 | Center |
| Spring Valley Sac Club | 2051 Northern Durham Parkway, Durham, NC 27703 | Center |
| Steps And Ladders Child Care Center | 1914 Taylor Street, Durham, NC 27703 | Center |
| The Greater New Birth Child Development Center | 2618 Harvard Ave, Durham, NC 27703 | Center |
| Victorious Day Care & Preschool Academy | 2116 Page Rd, Durham, NC 27703 | Preschool |
| Ye Smith Sac Club | 2410 E Main Street, Durham, NC 27703 | Center |