| Abbate's Day Care | 349 Blanding Boulevard, Orange Park, FL 32073 | Preschool |
| Advent Lutheran Preschool | 2156 Loch Rane Boulevard, Orange Park, FL 32073 | Preschool |
| Andromeda Preschool | 131 Suzanne Avenue, Orange Park, FL 32073 | Preschool |
| Apple Tree Academy Childcare | 1246 Park Avenue, Orange Park, FL 32073 | Center |
| Arora's Clubhouse | 330 Arora Boulevard, Orange Park, FL 32073 | Preschool |
| Belmont Head Start | 15 Belmont Blvd, Orange Park, FL 32073 | Preschool |
| Bright Start School and Daycare | 217 Wells Road, Orange Park, FL 32073 | Center |
| Challenge Enterprises Lighthouse Learning | 550 Kingsley Avenue, Orange Park, FL 32073 | Preschool |
| Childtime Learning Center | 2890 Moody Avenue, Orange Park, FL 32073 | Preschool |
| Grace Episcopal Dayschool | 156 Kingsley Avenue, Orange Park, FL 32073 | Center |
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| Grove Park Elementary School Preschool | 1643 Miller Street, Orange Park, FL 32073 | Preschool |
| Island View Baptist Child Care Center | 900 Park Avenue, Orange Park, FL 32073 | Preschool |
| Just Kids Learning Center | 120 Parkwood Drive East, Orange Park, FL 32073 | Preschool |
| Kampus Kids | 2300 Kingsley Avenue, Orange Park, FL 32073 | Preschool |
| Kids World of Florida | 2121 Constitution Drive, Orange Park, FL 32073 | Preschool |
| Oakleaf Village Elementary Preschool | 410 Oakleaf Village Parkway, Orange Park, FL 32073 | Preschool |
| Orange Park Presbyterian Church Preschool | 1905 Park Avenue, Orange Park, FL 32073 | Preschool |
| Orange Park's Little Miracles | 1981 Wells Rd, Orange Park, FL 32073 | Preschool |
| The Children's Corner | 1720 Smith Street, Orange Park, FL 32073 | Preschool |
| W E Cherry Elementary School Preschool | 420 Edison Drive, Orange Park, FL 32073 | Preschool |
| Wonderworks OPUMC | 2036 Reed Street, Orange Park, FL 32073 | Preschool |
| World of Wonders Academy | 101 Suzanne Avenue, Orange Park, FL 32073 | Preschool |
| YMCA Pryme Time at Argyle Elementary | 2625 Spencer Plantation Blvd, Orange Park, FL 32073 | Center |
| YMCA Pryme Time at Grove Park Elementary | 1643 Miller Street, Orange Park, FL 32073 | Center |
| YMCA Pryme Time at Lakeside Elementary | 2752 Moody Avenue, Orange Park, FL 32073 | Center |
| YMCA Pryme Time at Montclair Elementary | 2398 Moody Avenue, Orange Park, FL 32073 | Center |
| YMCA Pryme Time at Orange Park Elementary | 1401 Plainfield Avenue, Orange Park, FL 32073 | Center |
| YMCA Pryme Time at SB Jennings Elementary | 215 Corona Drive, Orange Park, FL 32073 | Center |
| YMCA Pryme Time at W.E. Cherry Elementary | 420 Edson Drive, Orange Park, FL 32073 | Center |