| Betty Sharp | 731 Euclid, Sikeston, MO 63801 | Center |
| Concordia Lutheran School | 836 Park Ave, Sikeston, MO 63801 | Center |
| Helping Hand Day Care | 124 N West St, Sikeston, MO 63801 | Center |
| Leslie Suzanne Karnes | 205 State Hwy Aa, Sikeston, MO 63801 | Center |
| Lil' Bulldogs Childcare Center | 307 N Prairie St, Sikeston, MO 63801 | Center |
| Little Einstein's Daycare | 1006 Maude St, Sikeston, MO 63801 | Center |
| Rainbow Day Care Center | 612 W North St, Sikeston, MO 63801 | Center |
| Scott County Central Early Learning Center | 20794 Us Highway 61, Sikeston, MO 63801 | Preschool |
| Sikeston Head Start | 115 S West St, Sikeston, MO 63801 | Preschool |
| Tracy Mccauley | 633 Greer St, Sikeston, MO 63801 | Center |
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| University Child Development Center | 2401 N Main St, Sikeston, MO 63801 | Center |
| YMCA of Southeast Missouri - 5th and 6th Grade Center | 100 Twitty Dr, Sikeston, MO 63801 | Center |
| YMCA of Southeast Missouri-lee Hunter Elementary | 315 Baker Ln, Sikeston, MO 63801 | Center |
| YMCA of Southeast Missouri-matthews Elementary | 604 Elm St, Sikeston, MO 63801 | Center |
| YMCA of Southeast Missouri-southeast Elementary | 2300 Ables Rd, Sikeston, MO 63801 | Center |
| YMCA of Southeastmissouri-kindergarten Center | 1310 E Salcedo Rd, Sikeston, MO 63801 | Center |