| ASU ABC New Life | 1105 North Terry, Wynne, AR 72396 | Center |
| ASU ABC Pre School Wynne | 1500 N. Lemons, Wynne, AR 72396 | Center |
| ASU ABC Wynne Odell McCallum Center | 325 Magnolia, Wynne, AR 72396 | Center |
| Apple of My Eye | 306 Hwy 1, Wynne, AR 72396 | Center |
| Ashleys Day Care | 249 Clifton Drive, Wynne, AR 72396 | Center |
| Caldwell Christian Academy | 1699 South Falls, Wynne, AR 72396 | Center |
| Debra Teeny Tots | 513 J Street, Wynne, AR 72396 | Center |
| Hogans Happy Time Dcc | 1042 West Garfield Apt D, Wynne, AR 72396 | Center |
| Kid Kare | 35 Cr 7415, Wynne, AR 72396 | Center |
| Little Hearts Big Pleasures | 806 Childress Drive, Wynne, AR 72396 | Center |
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| Little Sheep Day School | 1735 East Poplar, Wynne, AR 72396 | Center |
| Methodist Day School | 800 North Falls Blvd, Wynne, AR 72396 | Center |
| Mid - South Health Systems - Wynne | 1201 N Falls Blvd, Wynne, AR 72396 | Center |
| Miss Pollys Day Care | 613 N Church, Wynne, AR 72396 | Center |
| Nessa's Learning Center | 328 Holt St., Wynne, AR 72396 | Center |
| Vanessas CCFH | 330 Holt, Wynne, AR 72396 | Center |
| Wee School Wynne Baptist | 1200 Bridges St, Wynne, AR 72396 | Center |
| Wynne Community Enightenment Child Care Center | 102 Hamilton, Wynne, AR 72396 | Center |
| Wynne Head Start | 320 Magnolia St., Wynne, AR 72396 | Center |