| ABC Day School | 104 Pleasant Run RD W, Desoto, TX 75115 | Preschool |
| Blessed Are The Children | 2801 Prince George Ave, Desoto, TX 75115 | Preschool |
| Blessed Are The Children #2 | 1232 Beltline Rd. W, Desoto, TX 75115 | Preschool |
| CCF Academy | 524 W Beltline Rd, Desoto, TX 75115 | Preschool |
| Children of Promise Christian Academy | 106 Barrows Lane, Desoto, TX 75115 | Preschool |
| Clara Muhammad Academy | 1120 Beltline W, Desoto, TX 75115 | Preschool |
| Cross Of Christ Lutheran School | 512 Cockrell Hill N, Desoto, TX 75115 | Preschool |
| DeSoto Children's Academy | 901 Polk Ste 340 N, Desoto, TX 75115 | Preschool |
| DeSoto Private School & Day Care Center | 301 E Beltline Rd, Desoto, TX 75115 | Preschool |
| Discovery House | 105 Terrace St, Desoto, TX 75115 | Preschool |
|
| Excellence and Grace Private School | 1400 N Hampton Rd, Desoto, TX 75115 | Preschool |
| First Step Learning Center | 335 Hampton S, Desoto, TX 75115 | Preschool |
| Forest Park Academy | 2024 Westmoreland N, Desoto, TX 75115 | Preschool |
| Hampton Road Baptist Preschool | 400 Hampton Rd N, Desoto, TX 75115 | Preschool |
| Kids Are Us Private Learning Center | 1108 Westmoreland Rd N, Desoto, TX 75115 | Preschool |
| Kosmic Kids | 1101 Pleasant Run Rd E, Desoto, TX 75115 | Preschool |
| Learning Adventure Children's Center | 410 E Wintergreen Rd, Desoto, TX 75115 | Preschool |
| Nueva Vida Day Care DeSoto | 135 Wintergreen Rd W, Desoto, TX 75115 | Preschool |
| Park Ridge Academy | 415 Parkerville Rd. E, Desoto, TX 75115 | Preschool |
| Perfected Praise Child Care Center | 530 Reunion, Desoto, TX 75115 | Preschool |
| Pooh's Cottage | 107 Hampton Rd N, Desoto, TX 75115 | Preschool |
| Rainbow Children Center | 900 Beltline Road E, Desoto, TX 75115 | Preschool |
| Wee Care Youth & Recreation Center | 1670 N Hampton Rd Ste 115, Desoto, TX 75115 | Center |
| Windsor Park Primary School | 750 Pleasant Run Rd W, Desoto, TX 75115 | Preschool |