| Child Unlimited Inc | 1359 E COLLEGE, Seguin, TX 78155 | Preschool |
| Community Child Development Center | 1515 ENGBROCK, Seguin, TX 78155 | Preschool |
| Emanuel's Lutheran Day School | 310 N Travis, Seguin, TX 78155 | Preschool |
| Faith Lutheran Preschool | 1326 E Cedar, Seguin, TX 78155 | Preschool |
| First Baptist Early Learning | 1314 E CEDAR ST, Seguin, TX 78155 | Preschool |
| First United Methodist Weekday School | 710 N Austin, Seguin, TX 78155 | Preschool |
| Friedens Early Learning Academy | 2555 Friedens Church Rd, Seguin, TX 78155 | Preschool |
| Happy Hands In Home Christian | 210 RILL ROAD, Seguin, TX 78155 | Preschool |
| Headstart Central Guadalupe Co | 205 E Weinert St, Seguin, TX 78155 | Preschool |
| McCalls Daycare Center | 1733 Lullwood, Seguin, TX 78155 | Preschool |
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| Mini Mats Child Care Center | 1243 Cardinal Ln, Seguin, TX 78155 | Preschool |
| Rising Stars Learning Center | 855 Jefferson Avenue, Seguin, TX 78155 | Preschool |
| Sugar & Spice Early Birds | 1360 C.h. Matthies Jr. Dr. #1202, Seguin, TX 78155 | Preschool |
| Sugar and Spice Children's Academy #2 | 3569 N. 123 Bypass, Seguin, TX 78155 | Preschool |
| Sugar and Spice Childrens Academy | 311 E. Court, Seguin, TX 78155 | Preschool |