| Bearpaw KinderCare | 1 Bear Paw, Irvine, CA 92604 | Preschool |
| Childtime of Irvine | 4876 Irvine Center Drive, Irvine, CA 92604 | Preschool |
| Irvine KinderCare | 5396 Walnut Ave, Irvine, CA 92604 | Preschool |
| Chai Tots | 5010 Barranca Parkway, Irvine, CA 92604 | Preschool |
| Children's Center of St. Andrew's Episcopal Church | 4400 Barranca Parkway, Irvine, CA 92604 | Preschool |
| Dream Land Preschool | 5101 Walnut Avenue, Irvine, CA 92604 | Preschool |
| Good Shepherd Preschool | 4800 Irvine Center Drive, Irvine, CA 92604 | Preschool |
| IUSD Early Childhood Learning Center | One Smoketree, Irvine, CA 92604 | Center |
| Irvine Community Nursery School | 14341 Yale Avenue, Irvine, CA 92604 | Center |
| Irvine United Church Early Childhood Center | 4915 Alton Parkway, Irvine, CA 92604 | Preschool |
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| Jenny Hart Early Education Center | 4445 Alton Pkwy, Irvine, CA 92604 | Preschool |
| Leport Schools | 26 Lake Road, Irvine, CA 92604 | Preschool |