| Cambridge Child Development Center | 200 Lee Lane, Seneca, SC 29678 | Center |
| Code Learning Center | 315 A Holland Ave., Seneca, SC 29678 | Center |
| First Baptist Church Of Clemson Child Enrichment Center | 397 College Avenue, Clemson, SC 29631 | Center |
| Kids Kampus | 899 S Hwy 11, West Union, SC 29696 | Center |
| Kids Korner | 119 Windsor Street, Westminster, SC 29693 | Center |
| Kids Stuff Academy | 700 College Avenue, Walhalla, SC 29691 | Center |
| Kreative Kids Child Care | 1328 S Walnut Street, Seneca, SC 29678 | Center |
| Maxie Moms Daycare | 501 S. Fairplay St., Seneca, SC 29678 | Center |
| Oconee Christian Academy | 150 His Way Circle, Seneca, SC 29672 | Center |
| Our Clubhouse | 101 Nelson Drive, Seneca, SC 29678 | Center |
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| Seneca Baptist Child Care | 1080 South Oak Street, Seneca, SC 29678 | Center |
| Seneca Head Start Center | 340 N. Perkins Creek Rd., Seneca, SC 29678 | Center |
| St. Mark Child Development Center | 616 Quincy Road, Seneca, SC 29678 | Center |
| Tender Loving Child Care | 905 East Main Street, Walhalla, SC 29691 | Center |
| Trinity Baptist Preschool | 504 S. Oak Street, Seneca, SC 29678 | Center |