| A R K Cooperative Preschool | 400 Wayne St, Defiance, OH 43512 | Preschool |
| Close To Home | 955 Standley Rd, Defiance, OH 43512 | Center |
| Defiance Area YMCA School Age Child Care Program | 1599 Palmer Dr, Defiance, OH 43512 | Center |
| Family Resource Center Head Start | 648 Clinton Street, Defiance, OH 43512 | Center |
| First Impressions Daycare | 24515 Elliott Rd, Defiance, OH 43512 | Center |
| Heather's Day Care | 1700 Jefferson Ave, Defiance, OH 43512 | Center |
| Leaping and Learning Preschool And Child Care Center | 150 Grand Ave, Defiance, OH 43512 | Preschool |
| Poplar Ridge Training Station | 06970 Domersville Rd, Defiance, OH 43512 | Center |
| Rainbow Promise Day Care Center | 561 Carter Rd, Defiance, OH 43512 | Center |
| T&T's Little Angels Child Care Center | 08401 St.rt. 66 N, Defiance, OH 43512 | Center |