| Creative Days Child Care Center | 800 North Main Street, Roxboro, NC 27573 | Center |
| Early Intervention & Family Services | 1397 Hurdle Mills Road, Roxboro, NC 27573 | Center |
| Greater Children Development Center | 199 Flatriver Road, Roxboro, NC 27573 | Center |
| Helena Elementary School Age Care | 355 Helena Moriah Road, Timberlake, NC 27583 | Center |
| Learn & Play Children's Academy | 2081 Old Durham Road, Roxboro, NC 27573 | Center |
| Lester's Toddler Center | 703 Pearce St, Roxboro, NC 27573 | Center |
| North Elementary School Age Care | 260 Henderson Road, Roxboro, NC 27573 | Preschool |
| North End Elementary School Age Care | 378 Mill Creek Road, Roxboro, NC 27573 | Preschool |
| Piedmont Community College Child Development Center | 1715 College Drive, Roxboro, NC 27573 | Center |
| Rising Stars Learning Center | 739 Lucy Garrett Road, Roxboro, NC 27574 | Center |
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| Roxboro Christian Academy | 640 Johnson Street, Roxboro, NC 27573 | Center |
| Small World Day Care Of Timberlake | 324 Roby Barton Rd, Timberlake, NC 27583 | Center |
| Sneed Academy | 1191 Leasburg Road, Roxboro, NC 27573 | Center |
| South Elementary School Age Care | 1333 Hurdle Mills Road, Roxboro, NC 27573 | Center |
| Stories Creek Elementary School Age Care | 133 Stories Creek School Road, Roxboro, NC 27574 | Center |
| Woodland Elem Before & After School Childcare | 7391 Semora Road, Semora, NC 27343 | Center |