| Millers Creek KinderCare | 3774 Boone Trail, Millers Creek, NC 28651 | Center |
| Apple Tree Academies | 3774 Boone Trail Road, Millers Creek, NC 28651 | Center |
| Big Bird And The Gang | 775 Breeze Hill Rd, North Wilkesboro, NC 28659 | Center |
| Boomer Ferguson Elementary Pre Kindergarten | 556 Boomer Ferguson School Rd, Boomer, NC 28606 | Center |
| Broc Cub Creek Head Start | 1201 A Industrial Park Road, Wilkesboro, NC 28697 | Center |
| C C Wright Elementary School Prekindergarten | 200 C C Wright School Road, North Wilkesboro, NC 28659 | Center |
| CC Wright After School Fun Club | 200 Ccwright School Road, Wilkesboro, NC 28697 | Center |
| Double Trouble Early Learning Center | 600 Boston Avenue, North Wilkesboro, NC 28659 | Preschool |
| Easter Seals UCP Woodlawn Children's Center | 1302 Second St, North Wilkesboro, NC 28659 | Preschool |
| Gordon Baptist Church Christian School | 285 Boone Trail, North Wilkesboro, NC 28659 | Center |
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| Millers Creek After School Fun Club | 4320 North Hwy 16, Millers Creek, NC 28651 | Center |
| Millers Creek Child Care | 4120 Boone Trail, Millers Creek, NC 28651 | Center |
| Millers Creek Christian School | 5100 Old Boone Trail Road, Millers Creek, NC 28651 | Preschool |
| Moravian Falls Elementary Prekindergarten | 2001 Moravian Falls Road, Moravian Falls, NC 28654 | Preschool |
| Mountain View Elementary Prekindergarten | 5464 Mountain View Road, Hays, NC 28635 | Center |
| North Wilkesboro Elementary Prekindergarten | 200 Flint Hill Road, North Wilkesboro, NC 28659 | Center |
| Roaring River Elementary Pre Kindergarten | 283 White Plains Road, Roaring River, NC 28669 | Preschool |
| Safehaven Day Care Center | 707 Walker Street, Wilkesboro, NC 28697 | Center |
| The Children's Center Of Wilkes | 186 Bumgarner Road, Wilkesboro, NC 28697 | Center |
| Wilkes Family Central | 374 Lincoln Heights Road, Wilkesboro, NC 28697 | Center |
| Wilkesboro After School Fun Club | 1248 School Street, Wilkesboro, NC 28697 | Center |
| Wilkesboro Elementary School Prekindergarten | 1248 School Street, Wilkesboro, NC 28697 | Preschool |