| Fredericktown R I Preschool | 323 N Chamber Dr, Fredericktown, MO 63645 | Center |
| Kid's Corner Preschool | 400 S Chambers Dr, Fredericktown, MO 63645 | Preschool |
| Kountry Kidds | 400 Graham Dr, Fredericktown, MO 63645 | Center |
| Madison County Head Start | 600 S Chamber Dr, Fredericktown, MO 63645 | Preschool |
| Tiny Tots Daycare and Preschool | 106 Spruce St, Fredericktown, MO 63645 | Preschool |